Which fibrinolytics principally used in surgical procedures?

tenecteplase or reteplase

Enumerate the most prevalent side effects of fibrinolytic


Fibrinolytic agents are a class of medications used to dissolve blood clots. They work by breaking down fibrin, the protein that forms blood clots. Fibrinolytics are most commonly used to treat heart attacks and strokes, but they can also be used to treat other conditions such as pulmonary embolism and deep vein thrombosis.

The major toxicity of all thrombolytic agents is hemorrhage, which results from two factors: 
(1) the lysis of fibrin in “physiological thrombi” at sites of vascular injury; and 
(2) a systemic lytic state that results from systemic formation of plasmin, which produces fibrinogenolysis and destruction of other coagulation factors (especially factors V and VIII)


Other Side effects:

Headache 
Cerebral Haemorrhage 
Nausea
Fever 
Rash etc 


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